Epic Journey is a matter of perspective. I live in Rumney, and when I was assigned to a project in NYC last year, I took the train home to NH every other weekend. The investment was worth it to me to be home. If you're interested in public transit beta to make that trip happen, let me know via PM.
When I lived in Baltimore and DC, I'd drive to Seneca or The New. The key was that the payoff felt worth the 4-5 hour investment.